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如何解释mRNA水平升高，而蛋白表达下降

2025-04-06 19:27:29

推荐回答（1个）

回答1：

体存在生物钟.即以24小时为周期,许多基因的表达在这段时间里存在峰值(量多)和谷值(量少).因此您研究的基因如果有周期波动,您的结果就完全可能,因为有文献报告蛋白的表达比mRNA滞后3小时左右,因此您在现有的采样点后3小时再采样,可能蛋白表达量就与已有结果mRNA高一致.

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